Watch the full episode here - https://youtu.be/J736mfy7KEgFrom Modern Wisdom Podcast episode #066 PROFESSOR DAVID SINCLAIR | Can Humans Live For 1000 Years?-\r\rListen to all episodes online. Although Dr. Sinclair says there is no way of knowing for sure if 30 percent is the optimal caloric intake level, he also points out that there are now literally hundreds of experiments in animals showing lifespan extension by calorie restriction., RELATED READING: Dr. David Sinclairs Supplement List for Longevity, Theres a lot of evidence that exercise extends lifespan. In this episode, Dr. David Sinclair and co-host Matthew LaPlante discuss how frequently we should eat, what food we should avoid, and what food we should pursue. Exercise is a very important part of a healthy lifestyle as it brings an uncountable number of benefits that also include an increase in NAD+ levels. To me that sounds like the ultimate vacation! It includes various supplements such as. Thats basically true. Supplements Exercise is a very important part of a healthy lifestyle as it brings an uncountable number of benefits. Remember that intermittent fasting is a method of calorie restriction. Of course, looking younger for your age can be because you have good genes. However, mostly, it has to do with lifestyle. He religiously takes resveratrol, vitamin K2, NMN, metformin, and vitamin D3 on a regular basis. One of the lifestyle choices that Dr. David Sinclair implemented in his life is intermittent fasting (IF). Consider eating only one to two meals per day, exercising at a low intensity, and reducing or eliminating alcohol and meat to improve longevity. Think about it. Sinclair's approach is based on a broad view that links diseases of age such as cancer, diabetes, Alzheimer's, and heart failure to common cellular processes. I was recently diagnosed with pancreatitis. Its not all about food; exercise and social structure are associated with long lives. The protein will stop your hunger. He also drinks a green drink (Athletic Greens) in the morning so as to provide some nutrition to hold him till dinner. July 14, 2021 Thomas DeLauer. Eating meat is not going to kill you, but try to push yourself toward eating more plant based.. The changes in gene expression are closely related to longevity and protection against different diseases. He mixes resveratrol with yogurt in order to aid digestion. The following day I had pain on my right side and my stomach had a bulge on the right side. A mouse study showed that caloric restriction shortened the lifespan of more mice (based on genes) than it lengthened. Growing up, however, she found herself transitioning to non-fiction, psychological, and self-help books. Enjoyed reading this article when I read that my body mass was that of 109 year old woman I have to do something I am 76 years old so I know I have not one foot on a banana peel but both so I would like to save a few months of life. . If you want to eat meat, go for it. Every time you eat fruit, its like eating sugar because the fructose in the fruit turns into glucose very quickly, says Dr. Sinclair, who recommends eating green vegetables and blueberries every day to get the maximum levels of antioxidants in your diet. . We must fast to eat less often and regulate sirtuins, mTOR, and AMPK. Similar to any medical condition, David Sinclair believes that the aging process can be avoided and even cured. The less time you will spend with disease symptoms. I dont believe in exercise that is not strenuous, says Dr. Sinclair, who adds that people should try high-intensity interval training three times a week, working out at 85 percent of their maximum heart rate for about two minutes or until they are exhausted. I believe that the diet and exercise industry do more harm than good by instilling false hope of long term results. It will take about 30-45 minutes on a treadmill to work off a can of Coke. Disclaimer: These statements have not been evaluated by the Food and Drug Administration. The delicate dance of food consumption is at the heart of The Switch, a new book about new body-energy science and how it can help us live longer. Many prescription drugs are toxic and dangerous, says Dr. Sinclair, who believes that supplements can also play an important role in preventing damage from free radicals and promoting health. . They guide listeners towards a path to longer living by examining how we can change our eating habits to live longer, all while explaining the relevant science. That fasting or eating the right foods, like the Mediterranean diet not just to slows down the ticking of the clock, but probably reverses your age is a mind-blowing concept, says Dr. Sinclair. I got into zen trying and meditation and then zen body therapy figuring it would be good to learn a way to put the body back together again. I have been doing the IF for 6 weeks and I am so impressed with the results. Boca de Hurgano ( Spanish: [boka e weano]; Leonese: Boca de Grganu) is a municipality located in the province of Len, Castile and Len, Spain. Eating less glucose (when feeding yeast) increases their lifespan. In my experience (at least at my age), if we, In this video, Sinclair emphasizes that if you, He advocates reducing the amount of red meat and in particular processed meat. He mentions that TMAO promotes cancer and cardiovascular disease. What Might Help?Continue, Your email address will not be published. Now were retired on a farm in Idaho. Dr. Hahn graduated from Loma Linda University in 1994. Thanks much. He is currently the director of the Cardiovascular Fellowship Training Program at the Kettering Medical Center in Kettering Ohio. EIN 27-2656910, Our site uses cookies. Can Your Diet And Lifestyle Affect Your Vision. He has five main tips for doing so. In fact, Dr. Sinclair is a proponent of exercise and includes walking as part of his daily regimen. That would be about 1 day week! As you can see 3 of the 4 factors are low level stressors. My biggest regret is that gerontologists have been focusing so much money on a very, very few approaches to anti-aging research, says Dr. Sinclair, who urges people to explore lifestyle choices that have been proven effective in prolonging life. According to Dr. Sinclair, the best chance to live a longer life is closely related to eating healthy food and maintaining a balanced diet. Since so much of whats on the internet is BS is there a right and wrong way or a better way to do intermittent fasting that you can recommend? RELATED READING: Dr. Andrew Hubermans Time-Restricted Diet, Im a big proponent of the view that we seem to be getting more and more people focused on these high-tech anti-aging treatments, says Dr. Sinclair. Vitamin D3, Coenzyme Q10, Resveratrol, and TMG. Can you keep it up? Lifespan with Dr. David Sinclair | What to Eat & When to Eat for Longevity. YouTube.com, January 12th, 2022, https://www.youtube.com/watch?v=wD8reCw3Kls. But hes avoiding it for now.. If you want to live a long life, it all starts with those five servings.. . High amounts of amino acids such as leucine and isoleucine will switch on mTOR. Thank you for the information. 4-5 rounds of HIIT (about 2.5 minutes of hard work in a 20-25 minute exercise session) burns more calories, fat, and increased your metabolic rate more than 45 minutes of steady state running. As told by Dr. Sinclair, the takeaways of this podcast are to (1) eat less, (2) avoid sugar, (3) reduce meat intake, and (4) eat more of a plant-based diet, like the Mediterranean diet. It is important to remember that fasting is an eating pattern, not a diet. There may be benefits to eating plants that have experienced stress. According to studies, blueberries can help with aging, cancer, and DNA damage. The other great example is exercise. Meditation may even help to increase your longevity. Nils Osmar is an artist, writer, filmmaker, and teacher. Dr. Sinclair uses 1000mg of Metformin every day, apart from the days when he is exercising. But if they fast (whether or not they lose weight) they can get the same anti-aging benefits as people who are lean. So every day when youre fasting, says Dr. Sinclair, you use up part of your sugar and part of your fat. The more you sleep, the longer you are fasting, and the more calories you are burning! David Sinclair, Ph.D., A.O. 2. The trick, he says, is to fill yourself with fluids. The final longevity molecule discussed by David and Matthew was AMPK (AMP-activated kinase), an enzyme that goes up in response to low energy. Sinclair, David. The other stimuli that induces the production of BDNF is exercise. Alongside all of these benefits, shrimp is one of. Whichever source of resveratrol you choose, David believes that combining it with a fat source will boost its bioavailability. They say that the following people should not attempt intermittent fasting: People under 18 years old Pregnant or breastfeeding women People with metabolic disorders like diabetes People who suffer from eating disorders. Dr. Sinclair says that sugar is bad because it will reduce longevity, lead to type 2 diabetes, and possibly cause cardiovascular disease. We cover food, fasting and fitness. For example, if I set my daily calorie intake to 1500 calories a day and eat 1800 calories and burn 300 my net allowed caloric intake remaining for that day is 0. It is important to add foods to your diet that increase NAD+, a compound that helps to extend longevity. And that is not all, vitamin C in Kale is an excellent antioxidant and serves very important functions in the human body. I have hit a plateau which I am familiar with. The Prolon Fasting Mimicking Diet advocated by Dr. Valter Longo. In other words, with high sugar, your defenses against disease and aging are minimal. Its important to stay hydrated while fasting. The Harvard scientist explains that red meat is non-beneficial. Less, and more, are associated with increased cardiovascular events and death. Could Sirtuin 6 Activation Extend Lifespan in Humans? Plus, if you decrease your calorie intake, tons of cellular procedures are initiated. So far, I havent had any problems with IF. This video does contain a paid partnership with a brand that helps to support this channel. Working out in cold weather as it increases the immune system. However, it is important to note that Statin is not suitable for everyone, and before choosing to include it in your supplements stack, consult your doctor. Moreover, regular meditation, and expansion of thermoneutral zones (cold therapies). It also shows an effect on the immune system and lowers cortisol levels (also known as the stress hormone). It helps to reduce stress, relax more easily, and boost memory. He mentions that a study of elderly subjects in Spain showed that you could change your diet until the age of 80 and still get the benefits, so its not too late for many of us to change our eating habits to help us live longer lives. He believes that vast sums of money spent on life extension research would be better used for other purposes. Find your sleep sweet spot. Dr. Sinclair emphasizes that you cant take shortcuts when it comes to planning a diet and exercise regimen-the best way to prolong life expectancy is to eat st healthy balanced diet food, taking care not to overload your body with fructose or simple sugars. Hello100 is a life science company researching the mechanisms of healthy aging and life extension. It includes various supplements such as NMN, Vitamin D3, Coenzyme Q10, Resveratrol, and TMG. What do you call running on a treadmill in the fat burning zone for 30 min everyday? We often see that people who look considerably younger for their age have the following things in common: Professor David Sinclair is a shining example of these important longevity lifestyle factors. In the second podcast based on his book LifeSpan, Dr. Sinclair talks about the science behind how fasting and eating certain foods promote longevity. [], Full Transcript Grace: Welcome everyone! One, currently popular dietary technique that integrates all 3 of these areas is intermittent fasting. [Learn More. 10 Healthy Tips From Longevity Expert Dr. Shigeaki Hinohara. Choose higher-intensity exercise (HIIT workouts are recommended). He drinks little to no alcohol . Glucose attaching to protein will give increase AGEs. Focusing on less carbs and becoming ketoic sells better. Some of his key points this time: He mentions several approaches to fasting, all of which lower mTOR and activate AMPK. RELATED READING: Dr. David Sinclair's Anti-Aging Protocol Fasting Time Period The crux of Dr. Huberman's diet is the fasting time period. Plus, research done on humans has displayed benefits with a 12% calorie restriction too. Scientific research has repeatedly discovered a link between calorie consumption and long life. We have all seen, or even experienced the destruction that goes along with chronic stress from a terrible job, family illness, money worries, etc. He Practices Intermittent Fasting David believes that constant snacking is not the best way to prolong life expectancy. Bright colors indicate that they have survived stress and may be high in compounds that help activate the sirtuin genes. Follow Along with the Transcript. On today's video Dr. andrew huberman and dr. david sinclair they explain everything about fasting, what breaks the fast, how to optimize it and much more. This article will be shared with my group and will give you and the researchers props!. Instead of focusing mainly on what you eat, it is more about when you are eating your meals. It increases cell survival, it enhances metabolic pathways (better glucose and cholesterol maintenance), increase mitochondrial function and energy production, and increases the production of brain derived neurotrophic factor (BDNF) which improves brain function. I love listening to Sinclair and have learned a lot from him. According to scientific research, high blood sugar quickens the aging clock. On his runs he drinks a high carb drink that is more concentrated than the typical sports drink. If you do not allow a time of recovery then there will be limited or no benefit. Eat Stop Eat Skip eating for some days each week. While low level stress typically aids in focus and concentration. These pills truly enhance the lifespan. One person had cut back his diet to 800 calories a day and was still gaining weight! You can read up on David Sinclairs Supplement Regime here. So no fruit juice or sugar in the morning, Dont eat a big bowl of ice cream every night (but its okay to have a few bites), Avoid super-high protein. Nowadays meditation can be adapted with a lot of help from various sources. Why eat less often? 20% off with code THOMAS - Try Verso NMN Today: https://ver.so/. The big three areas of healthy living are diet, exercise, and sleep. It Didnt Start With You: Book Overview & Takeaways, Theranos: Walgreens Deal Was Doomed From the Start, How Does the Brain Learn Best? Sinclair has been skipping breakfast since he was a teenager (though he does take a couple of spoons of yogurt in the morning to make sure his supplements are absorbed). So is there a way that we can more easily tap into fat without running for 2 hours a day? I am educating them on health and the benefits of Intermittent fasting. NAD+ was shown to increase the lifespan of yeast, which is one of the reasons why so many people now take NR (nicotinamide riboside) and NMN (nicotinamide mononucleotide) supplements, which boost NAD+ levels. David Sinclair uses intermittent fasting in his daily practice. The subjects could pick whatever times of the day to eat during as long as it was continuous. Those constant (not intermittent) stressor lead to the breakdown of the human mind, body, and spirit. David Sinclair is a now professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School. Moreover, regular meditation, and expansion of thermoneutral zones (cold therapies). . Thank you for this article,I have been at the right weight for 22 years ( I was 210 now 115) I eat no sugar or flour nothing processed.But My LDL levels have gone up consistently for the last 10 years ,it is 230 now,my HDL is 75.My doctor and I have decided to try this 16:8 eating plan and retest me in 2 weeks .I have my fingers crossed .My question is have you seen this help in other people and can you make any suggestions?
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