Information from this source is evidence-based and objective, and without commercial influence. BJU Int 2000;85:481-5. Life Sci 1993;53(5):PL63-8. Not too many side effects of peony tea that we need to worry about. Effects of the licorice extract against tumor growth and cisplatin-induced toxicity in a mouse xenograft model of colon cancer. View abstract. Some of these health benefits have also . Li G, Simmler C, Chen L, et al. Nahidi F, Zare E, Mojab F, Alavi-Majd H. Effects of licorice on relief and recurrence of menopausal hot flashes. Some medications are changed and broken down by the liver. This plant is native to East Asia. Taking peony along with birth control pills might increase the risk of side effects. Aging Clin Exp Res. Panduranga P, Al-Rawahi N. Licorice-induced severe hypokalemia with recurrent torsade de pointes. Brayley J, Jones J. Life-threatening hypokalemia associated with excessive licorice ingestion (letter). View abstract. Kinoshita, H., Okabayashi, M., Kaneko, M., Yasuda, M., Abe, K., Machida, A., Ohkubo, T., Kamata, T., and Yakushiji, F. Shakuyaku-kanzo-to induces pseudoaldosteronism characterized by hypokalemia, rhabdomyolysis, metabolic alkalosis with respiratory compensation, and increased urinary cortisol levels. Phytother Res 1988;2(3):140-145. Lee, S. J., Lee, I. S., and Mar, W. Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 activity by 1,2,3,4,6-penta-O-galloyl-beta-D-glucose in murine macrophage cells. Kumada T, et al. View abstract. Some medications are changed and broken down by the liver. View abstract. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. Cancer 1997;79(8):1494-1500. Nasal irrigation with Glycyrrhiza glabra extract for treatment of allergic rhinitis - A study of in vitro, in vivo and clinical trial. . Early evidence suggests that taking 45 grams of a specific product containing peony and licorice (Peony-Glycyrrhiza Decoction, PGD) daily for 4 weeks reduces levels of a hormone called prolactin in women with high levels of prolactin, without affecting other hormone levels or mental symptoms. View abstract. The U.S. Food and Drug . However, taking too much licorice root may cause side effects. Guo, D., Ye, G., and Guo, H. A new phenolic glycoside from Paeonia lactiflora. Cumming, A. M., Boddy, K., Brown, J. J., Fraser, R., Lever, A. F., Padfield, P. L., and Robertson, J. I. Hataya Y, Oba A, Yamashita T, Komatsu Y. Hyponatremia in an elderly patient due to isolated hypoaldosteronism occurring after licorice withdrawal. View abstract. View abstract. Br Med J 9-17-1977;2(6089):738-739. J Gastroenterol 1996;31(5):691-695. View abstract. Qi XG. It has an effect similar to aldosterone. Johns, C. Glycyrrhizic acid toxicity caused by consumption of licorice candy cigars. View abstract. View abstract. Man SC, Li XB, Wang HH, et al. Effect of glycyrrhizin-containing toothpaste on dental plaque reduction and gingival health in humans. Loop diuretics can also decrease potassium levels. Maeda T, Shinozuka K, Baba K, et al. View abstract. The author has contributed to research in topic(s): Rheum officinale. Phytother Res 2012;26(9):1381-1384. Eur J Clin Pharmacol 2010;66(8):805-810. View abstract. View abstract. Yoshino T, Yanagawa T, Watanabe K. Risk factors for pseudoaldosteronism with rhabdomyolysis caused by consumption of drugs containing licorice and differences between incidence of these conditions in Japan and other countries: case report and literature review. View abstract. Menopause 2002;9:145-50. View abstract. Hasani-Ranjbar, S., Nayebi, N., Moradi, L., Mehri, A., Larijani, B., and Abdollahi, M. The efficacy and safety of herbal medicines used in the treatment of hyperlipidemia; a systematic review. View abstract. 2000;19(8):434-439. Melzer J, Rosch W, Reichling J, et al. Bardhan, K. D., Cumberland, D. C., Dixon, R. A., and Holdsworth, C. D. Clinical trial of deglycyrrhizinised liquorice in gastric ulcer. Sakamoto, S., Yoshino, H., Shirahata, Y., Shimodairo, K., and Okamoto, R. Pharmacotherapeutic effects of kuei-chih-fu-ling-wan (keishi-bukuryo-gan) on human uterine myomas. This fragrant, perennial plant -- a member of the celery family -- has smooth purplish stems and umbrella-shaped clusters of white flowers and winged fruits in July and August. Neth J Med 2005;63:149-50. Cardiovasc.Drugs Ther 1998;12(6):599-600. Hsiang, C. Y., Hsieh, C. L., Wu, S. L., Lai, I. L., and Ho, T. Y. Inhibitory effect of anti-pyretic and anti-inflammatory herbs on herpes simplex virus replication. Hossain, M. S., Takimoto, H., Hamano, S., Yoshida, H., Ninomiya, T., Minamishima, Y., Kimura, G., and Nomoto, K. Protective effects of hochu-ekki-to, a Chinese traditional herbal medicine against murine cytomegalovirus infection. Yasue H, Itoh T, Mizuno Y, Harada E. Severe hypokalemia, rhabdomyolysis, muscle paralysis, and respiratory impairment in a hypertensive patient taking herbal medicines containing licorice. Sun, W. S., Imai, A., Tagami, K., Sugiyama, M., Furui, T., and Tamaya, T. In vitro stimulation of granulosa cells by a combination of different active ingredients of unkei-to. CJEM 2009;11(1):94-96. Cancer Res 2000;60:5704-9.. View abstract. Gardner Z, McGuffin M. Boca Raton, FL: CRC Press, 2013. Complement Ther Med. View abstract. View abstract. Purnak, T., Ozaslan, E., Beyazit, Y., and Haznedaroglu, I. C. Upper gastrointestinal bleeding in a patient with defective hemostasis successfully treated with ankaferd blood stopper. J Clin Ther Med 1999;15:499-523. In some cases, this might change the effects and side effects of a medication. An Med Interna 1995;12(1):33-35. Ngan LT, Moon JK, Shibamoto T, Ahn YJ. Helpful. View abstract. Chang GH, Lin YS, Hsu KH, et al. Low potassium levels can increase the side effects of digoxin. Baba, M. and Shigeta, S. Antiviral activity of glycyrrhizin against varicella-zoster virus in vitro. Hasegawa, J., Suyama, Y., Kinugawa, T., Morisawa, T., and Kishimoto, Y. Echocardiographic findings of the heart resembling dilated cardiomyopathy during hypokalemic myopathy due to licorice-induced pseudoaldosteronism. Sucking on a licorice lozenge or gargling with a licorice fluid shortly before placement of a breathing tube seems to help prevent cough and. View abstract. Licorice is an herb that grows in parts of Europe and Asia. Zhongguo Zhong.Xi.Yi Jie.He.Za Zhi 2008;28(4):358-360. Eisenburg, J. View abstract. View abstract. Z., Zhang, Y. View abstract. Cytochrome P450 inhibition by three licorice species and fourteen licorice constituents. Herb-Drug Interaction Potential of Licorice Extract and Paclitaxel: A Pharmacokinetic Study in Rats. Constituent properties of licorices derived from Glycyrrhiza uralensis, G. glabra, or G. inflata identified by genetic information. View abstract. View abstract. Bisogni V, Rossi GP, Cal LA. Alt Med Rev 2001;6:495-9. 1979;14(5):605-607. Zhang W, Leonard T, Bath-Hextall F, et al. View abstract. Read about Peony uses, side effects, health benefits, interactions, dose, warnings, and precautions. Complement Ther Clin Pract. Health Care Women Int. View abstract. J Ethnopharmacol. Wu G, Wu N, Li T, et al. Armanini D, Bonanni G, Palermo M. Reduction of serum testosterone in men by licorice. Peters, M. C., Tallman, J. Wang H, Wei W, Wang NP, et al. View abstract. J Cosmet.Sci 2006;57(1):57-64. Medicinal uses of licorice through the millennia: the good and plenty of it. Arentz S, Smith CA, Abbott J, Fahey P, Cheema BS, Bensoussan A. Chamberlain, J. J. and Abolnik, I. View abstract. Kent UM, Aviram M, Rosenblat M, Hollenberg PF. View abstract. Bruynzeel DP. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. View abstract. View abstract. Prospective study]. View abstract. Z Gastroenterol 2001;39(7):511-7. Lee, C. H., Park, S. W., Kim, Y. S., Kang, S. S., Kim, J. Gao, X., Wang, W., Wei, S., and Li, W. [Review of pharmacological effects of Glycyrrhiza radix and its bioactive compounds]. The efficacy and safety of total glucosides of peony in the treatment of primary Sjögren's syndrome: a multi-center, randomized, double-blinded, placebo-controlled clinical trial. J Ethnopharmacol 2002;81:101-4.. View abstract. Pharm Biol 2021;59(1):1276-1285. Information from this source is evidence-based and objective, and without commercial influence. A multicentre trial. Planta Med 1983;48(5):38-42. 2018;38(2):617-8. Dellow EL, Unwin RJ, Honour JW. N Engl J Med 1991;325:1223-7. View abstract. Kinoshita T, Maruyama K, Yamamoto N, Saito I. Fitoterapia 2006;77(7-8):613-614. Int J Environ Res Public Health 2021;19(1):242. Yamada, K., Kanba, S., Yagi, G., and Asai, M. Effectiveness of herbal medicine (shakuyaku-kanzo-to) for neuroleptic-induced hyperprolactinemia. Case Rep Emerg Med. View abstract. View abstract. 2020;50:102401. B. Licorice-associated reversible cerebral vasoconstriction with PRES. and its bioactive compounds. J Clin Periodontol 1991;18(3):210-212. Medicine (Baltimore) 2019;98(35):e16601. J Clin Hypertens (Greenwich) 2008;10:153-7. View abstract. Zangooei Pourfard M, Mirmoosavi SJ, Beiraghi Toosi M, et al. Exp Neurol 1997;146:518-25. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. View abstract. I. Elucidation of five new flavonoid constituents from the roots of Glycyrrhiza glabra L. collected in Xinjiang. Hukkanen J, Ukkola O, Savolainen MJ. J Assoc Physicians India 1978;26(9):811-814. Am J Chin Med 2005;33(5):747-758. View abstract. Licorice or Mulethi, also known as "Sweetwood", is an effective and potent medicinal herb. J Pharm Pharmacol 2003;55:1275-82. Riv Patol Nerv Ment 1983;104(4):179-183. Z. Plant Description. Werner, S., Brismar, K., and Olsson, S. Hyperprolactinaemia and liquorice. View abstract. Arch Pharm Res 2002;25(3):293-299. Monitor your blood pressure closely. 1994;14:207-9, 195. . Microbiol Immunol 2000;44(9):799-804. Farese RV Jr, Biglieri EG, Shackleton CH, et al. Am.J Chin Med 2004;32(4):569-578. Hyodo T, Taira T, Kumakura M, et al. Large amounts of licorice can decrease potassium levels in the body. Benge E, Shah P, Yamaguchi L, Josef V. Trick or Treat? [Effectiveness of interferon, glycyrrhizin combination therapy in patients with chronic hepatitis C]. 2014 Jun;20(6):516-20. Guo TL, Zhou XW. View abstract. View abstract. A controlled trial of traditional Chinese medicinal plants in widespread non-exudative atopic eczema. Murakami, T. and Uchikawa, T. Effect of glycyrrhizine on hyperkalemia due to hyporeninemic hypoaldosteronism in diabetes mellitus. Ultrastruct Pathol 1992;16(5):529-535. 2005;25(6):540-542. Lower potassium levels can cause those abnormal heart arrhythmias. View abstract. J Pharmacobiodyn 1983;6:153-60. . For people who already have high blood pressure or heart or kidney disease, as little as 5 g/day can cause these side effects. Zhou Y, Jin L, Kong F, et al. Clinical trial of deglydyrrhizinized liquorice in gastric ulcer. 2017 Sep;31(9):1330-1340. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Mol Cell Endocrinol. Pak J Med Sci 2022;38(1):271-275. View abstract. Arentz S, Smith CA, Abbott J, Fahey P, Cheema BS, Bensoussan A. Eur Neurol 1992;32(1):44-51. View abstract. A preliminary open trial on interferon stimulator (SNMC) derived from Glycyrrhiza glabra in the treatment of subacute hepatic failure. Some believe it may also increase estrogen and prolactin levels in women, though more research is warranted. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. View abstract. Double-blind, placebo-controlled, randomized, pilot clinical trial of ImmunoGuard--a standardized fixed combination of Andrographis paniculata Nees, with Eleutherococcus senticosus Maxim, Schizandra chinensis Bail. View abstract. Paeoniflorin: an antihyperlipidemic agent from Paeonia lactiflora. Ann Mtg Digestive Disease Week 1999 May. Int J Nurs Stud 2016;63:9-17. 2007;30(10):1898-1904. Astragalus may be safe when used orally and appropriately. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Treatment of duodenal ulcer with glycyrrhizinic-acid-reduced liquorice. Effect of glycyrrhizin on viral replication and quasispecies in patients with type C chronic hepatitis. J Med Liban 2012;60(2):117-119. Nabeshima, S., Kashiwagi, K., Ajisaka, K., Masui, S., Takeoka, H., Ikematsu, H., and Kashiwagi, S. A randomized, controlled trial comparing traditional herbal medicine and neuraminidase inhibitors in the treatment of seasonal influenza. Peony (Paeonia lactiflora) is an herb. Yoon JY, Cha JM, Hong SS, et al. A dual investigation of the effect of dietary supplementation with licorice flavonoid oil on anthropometric and biochemical markers or health and adiposity. Attou R, Redant S, Honore PM, Preseau T, Hantson P, De Bels D. Liquorice intoxication can lead to cardiac arrest! View abstract. 1993;13(10):591-3, 579. Zhong Xi Yi Jie He Za Zhi 1991;11(3):150-2, 133. Side effects, toxicity, and interactions. Glycyrrhizin-Induced Pseudohyperaldosteronism: A Case Report. Title 21. 1991;11(4):199-202, 195. Motherwort, Peony, Dong Quai, Lady's Mantle, Licorice, and Rose, Fennel, Alfalfa. Gomaa AA, Mohamed HS, Abd-Ellatief RB, Gomaa MA, Hammam DS. A., Torres Murillo J., and Calderon de la Barca Gazquez J. M. [Acute rhabdomyolysis and tetraparesis secondary to hypokalemia due to ingested licorice]. Aoki, F., Nakagawa, K., Kitano, M., Ikematsu, H., Nakamura, K., Yokota, S., Tominaga, Y., Arai, N., and Mae, T. Clinical safety of licorice flavonoid oil (LFO) and pharmacokinetics of glabridin in healthy humans. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. A., van Dokkum, W., and Savelkoul, T. J. Glycyrrhizic acid: the assessment of a no effect level. View abstract. Quinkler M, Stewart PM. Zhongguo Zhong Xi Yi Jie He Za Zhi 2008;28(4):314-317. Oh, G. S., Pae, H. O., Choi, B. M., Lee, H. S., Kim, I. K., Yun, Y. G., Kim, J. D., and Chung, H. T. Penta-O-galloyl-beta-D-glucose inhibits phorbol myristate acetate-induced interleukin-8 [correction of intereukin-8] gene expression in human monocytic U937 cells through its inactivation of nuclear factor-kappaB. N Engl J Med 1968;278(25):1381-1383. Evaluation of contextual and demographic factors on licorice effects on reducing hot flashes in postmenopause women. Beretta-Piccoli, C., Salvade, G., Crivelli, P. L., and Weidmann, P. Body-sodium and blood volume in a patient with licorice-induced hypertension. Effects of glycyrrhizin on biochemical tests in patients with chronic hepatitis -- double blind trial. View abstract. View abstract. Myopathies associated with red yeast rice and liquorice: spontaneous reports from the Italian Surveillance System of Natural Health Products. A., Lee, S. H., and Lee, S. M. Protective mechanism of glycyrrhizin on acute liver injury induced by carbon tetrachloride in mice. Rees, W. D., Rhodes, J., Wright, J. E., Stamford, L. F., and Bennett, A. View abstract. Clinical application of compound Glycyrrhizin tablets in the treatment of patients with Simplex Henoch-Schonlein Purpura and its effect on immune function. View abstract. This information may not fit your specific health circumstances. Cooper, H., Bhattacharya, B., Verma, V., McCulloch, A. J., Smellie, W. S., and Heald, A. H. Liquorice and soy sauce, a life-saving concoction in a patient with Addison's disease. View abstract. J Contemp Dent Pract 2010;11(1):E088-E094. Intern Med 2007;46:575-8. Select a condition to view a list of vitamins. Paeonia lactiflora (Chinese peony) and Paeonia brownii (California peony) relax smooth muscle tissue with a particular affinity for the female reproductive tract. Influence of traditional Chinese anti-inflammatory medicinal plants on leukocyte and platelet functions. A specific type of peony product, total glucosides of peony (TGP), has most often been used by adults in doses of 600 mg by mouth three times daily for up to 24 weeks. Teelucksingh S, Mackie AD, Burt D, McIntyre MA, Brett L, Edwards CR. Epilepsy Res 2021;176:106735. Armanini D, Lewicka S, Pratesi C, et al. Best Underarm Whitening Creams For You 1. Mumoli, N. and Cei, M. Licorice-induced hypokalemia. Celik, M. M., Karakus, A., Zeren, C., Demir, M., Bayarogullari, H., Duru, M., and Al, M. Licorice induced hypokalemia, edema, and thrombocytopenia. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. J Endocrinol Invest 2003;26:646-50. It contains kojic acid, witch hazel, and licorice extracts that reduce melanin production and exfoliate . Anti Erection Pill. Removes excess melanin: Licorice extract brightens the skin in another way, too. A newly-filed federal lawsuit claims eating too much of The Hershey Company's Good & Plenty and black licorice Twizzlers candies can cause serious health problems, maybe even death. Crean, A. M., Abdel-Rahman, S. E., and Greenwood, J. P. A sweet tooth as the root cause of cardiac arrest. View abstract. Pseudohyperaldosteronism, liquorice, and hypertension. Therapeutic basis of glycyrrhizin on chronic hepatitis B. Antiviral Res 1996;30:171-7. J Pharmacol Exp Ther 2006;316:1369-77. Chewing tobacco flavored with Licorice may cause serious side effects such as high blood pressure. Glycyrrhizin, an active component of liquorice roots, and replication of SARS-associated coronavirus. 2019;38(3):657-64. Combined Lifestyle and Herbal Medicine in Overweight Women with Polycystic Ovary Syndrome (PCOS): A Randomized Controlled Trial. Oh, G. S., Pae, H. O., Choi, B. M., Jeong, S., Oh, H., Oh, C. S., Rho, Y. D., Kim, D. H., Shin, M. K., and Chung, H. T. Inhibitory effects of the root cortex of Paeonia suffruticosa on interleukin-8 and macrophage chemoattractant protein-1 secretions in U937 cells. View abstract. PCOS; Fertility; 25 - 45; Menopause; 45 - 60; Pregnancy Sigurjonsdottir HA, Ragnarsson J, Franzson L, Sigurdsson G. Is blood pressure commonly raised by moderate consumption of liquorice? Asian Medical Journal 1984;26(7):423-438. Yoshida S, Takayama Y. Licorice-induced hypokalemia as a treatable cause of dropped head syndrome. [Clinical observation on auxiliary treatment of hormone dependence dermatitis by shufeng liangxue decoction]. The inhibition of phenylhydroquinone-induced oxidative DNA cleavage by constituents of Moutan Cortex and Paeoniae Radix. Let's take a look at the forms, uses, and side effects of . Paeoniflorin's. View abstract. Licorice can decrease potassium levels. 2020;2020:8401239. View abstract. Paeoniflorin, a constituent of white peony root, has demonstrated inhibition of testosterone synthesis in vitro, without affecting estradiol synthesis.It reduces testosterone production by the ovaries but not the adrenal glands. View abstract. Gallacher SD, Tsokolas G, Dimitropoulos I. Liquorice-induced apparent mineralocorticoid excess presenting in the emergency department. Heavy consumption of licorice during pregnancy has been associated with premature birth and health problems in the child. Mechanisms involved in the therapeutic effects of Paeonia lactiflora Pallas in rheumatoid arthritis. The immediate effect of Shakuyaku-kanzo-to, traditional Japanese herbal medicine, for muscular cramps during maintenance hemodialysis.
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