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grey, gray, feet bobby bomb, When used, deals damage to Isaac in exchange for +1.2 damage up which lasts for the current room, The first use per room takes 1 full heart, then 0.5 hearts per use after that. This is a one-time use of the Red Key item. red, drip, Isaac's health is set to 1 and he also gains 9 extra lives, Each time Isaac dies, he will respawn with 1 Health, Has a chance to drop from the Super Pride mini boss, The floating Dead Cat head that follows you will disappear when you are on your last life (Very useful for The Lost), Counts as 1 of 3 cat items needed towards the Guppy transformation, Item Pool: Devil Room, Curse Room, Red Chest, Super Pride Miniboss, * curse room pool, red chest pool, red chest item pool, devil pool, devil room pool, devil deal, Gives Isaac demon wings and the ability to fly. - The Binding Of Isaac: Repentance #50; DOUBLE DEATH (CERTIFICATE)! e.g. Can only happen once per room, Visually this is almost identical to the Guardian Angel item, but without a face, UNLOCK: Unlock this item by beating Blue Womb (Hush) with The Lost, A white orbiting fly which deals 3 contact damage per tick to enemies, This familiar orbits Isaac at a middle length distance somewhere between Distant Admiration and Forever Alone, Item Pool: Item Room, Greed Mode Item Room, Key Beggar. Lazarus - Every time Lazarus dies, gives +21.6 temporary Damage Up, gradually fading over 1 minute. black, white, gray, grey, guppys tail, guppy tail, Upon use, the IV Bag takes half a red heart and spawns 1-3 coins (the same effect as a blood donation machine), Can drop from a blood donation machine after playing it, In the Womb and beyond this deals 1 full heart of damage, If no red hearts exist, other types of hearts are consumed instead, With the Keeper this is changed to spawning 0-1 coins per use instead, Item Pool: None (Blood donation machine only), Places a decoy on the floor which attracts enemies and explodes after a period of time, When it explodes, it deals 185 damage to everything in radius (Same damage as Mr Mega bombs), * item room, treasure room, item room pool, worst friend, dead, baby, pink, puppet, Bombs no longer automatically explode and will only do so when you activate the remote detonator, Can be used to detonate Dr. Fetus bombs early, * boss rush pool, boss rush room, shop room pool, shop item pool, item room, treasure room, Some items are passive, which add an effect permanently to Isaac, while others only activate when used. paper, roll, white, All of Isaac's bombs now having a homing effect when placed on the floor, * boss rush pool, boss rush room, item room, treasure room, item room pool, bomb beggar, dead, The pick-ups which are NOT items, are the Pills, Tarot Cards and Trinkets. Tags: Items, Active Items, Graphics. Poison, Homing, Prize Bombs), In Antibirth this was called Enigma Bombs, Spawns a red worm familiar that chases enemies nearby around the room and deals 2 contact damage per tick. Sort: Item ID Colour Alphabetical Isaac Cheat Sheet. character damage multipliers), This item can only reduce your heart containers and will not increase them if you change back into a character with more health. Pretty Fly gives a Big Fan item rather than a fly orbital, UNLOCK: Unlock this by defeating Mega Satan as Tainted Eve, 1 Dot - Rerolls all of your items. Isaac takes a full heart if hurt by Blood Puppy and it drops a full red heart for every 10 enemies it kills. - Spawns the last pill you used. When the effect wears off, Isaac quickly runs between each marked enemy, dealing high damage to each one rapidly (roughly x2.5 your tear damage), The damage caused by this effect scales up with every target it hits in a row, UNLOCK: Unlock this item by defeating Delirium as Tainted Judas, *, budas, jubas, sword, blood, omae wa mou shindeiru, When used, Abyss consumes all pedestal items in the current room and converts them into Red attack flies, Red attack flies will charge across the room in the same direction Isaac is shooting, dealing contact damage to enemies equal to Isaac's tear damage, The flies don't block enemy shots, but this also means they never die and stay with Isaac forever, UNLOCK: Unlock this item by defeating Delirium as Tainted Apollyon, Staples one of Isaac's eyes shut, meaning he only shoots tears from one eye. The Mega Mush is a new mushroom-type item in The Binding Of Isaac: Repentance and, like the other mushrooms, significantly affects the player's stats. If you haven't unlocked Holy Mantle for The Lost yet, you won't gain the effect after touching a white fire so be careful! After reaching level 4 (and at a much lower chance before level 4), Bumbo will also continue to collect coins and drop random pickups, similar to the Bum Friend item, but can also drop pedestal items very rarely. I've redone some of the TBOI's items, here's a showcase of just 4 of ones I've changed (right now I've modified a total of 19 items), which I personally think needed a change. ), UNLOCK: Unlock this item by beating Blue Womb (Hush) with Cain, Gives Isaac a familiar golden Censer which creates a huge aura of light that slows down any enemies inside it, UNLOCK: Unlock this item by beating Greed Mode with Maggy, A familiar beggar similar to Bum Friend that follows Isaac and collects keys, giving random chests in return, UNLOCK: Unlock this item by beating Greed Mode with Lazarus, Item Pool: Item Room, Secret Room, Key Beggar, *, grey, gray, black, face, stone, rock, baby, A bag that follows Isaac and drops a random Rune or Soul Stone every 7 or 8 rooms, UNLOCK: Unlock this item by beating the Isaac boss with Lilith, A familiar angel which follows Isaac and fires Sacred Heart tears which deal 10 damage at -25% shot speed and a reduced fire rate, Item Pool: Item Room, Angel Room, Greed Mode Angel Room, This item causes enemy projectiles to be able to hit other enemies. poop, pots, TNT, red poop, stone blocks, spikes, fireplaces etc. UNLOCK: Unlock this item by defeating Lil Horn 20 times, When picked up, gives Isaac a random familiar which has a random sprite and tear effect, The familiar will be fully randomized again upon entering the next floor, The appearance is chosen from a random co-op baby sprite, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Ashkait and Scayze, A familiar that will transform into another random familiar every 10 seconds, copying their behaviour and effect, Can be any other familiar, including (but not limited to) Lil Brimstone, Bob's Brain, BBF, Meatboy, Rotten Baby, Familiars appear as a white Delirium version of the original, This item gives you 1 bar of charge on your active item for every 15 enemies you kill, Added as part of the Afterbirth+ Booster Pack #2 and based on the Steam Workshop mod created by Ashkait and Scayze, UNLOCK: Unlock this item by picking up any 3 of these items in a single run: 9 Volt, The Battery, Car Battery, AAA Battery, Watch Battery, When used, the coupon causes one random item in the shop to become free, While held, guarantees a random item or pickup from the shop to be half price, The effect of this item also works in Devil Rooms, allowing you to take one random item for free, Added as part of the Afterbirth+ Booster Pack #2 and based on the Steam Workshop mod created by Plumbo, *, paper, square, green, pink, white, barcode, letter, postcard, An active that causes all enemy tears to be held in place and then thrown back away from Isaac for a period of 3 seconds, The aura from this item will repel nearby enemies, Added as part of the Afterbirth+ Booster Pack #2, When used, the box will pick up a maximum of 6 items. All floors guaranteed to have an Arcade except the Chest & Dark Room floors, Judas - Gives a passive Book of Belial item similar to Book of Virtues. To help with range, the orbit is now also offset based on the current direction Isaac is shooting, * item room, treasure room, item room pool, grey, gray, asteroid, silver, ball, Creates a friendly blue spider when you kill an enemy, Spiders are spawned at the location where the enemy died, * item room, treasure room, item room pool, pink, smile, E. Coli turns normal enemies into poop if they touch you, Enemies can turn into poop even if they do not do contact damage, allowing you to apply the effect without taking damage, Can be combined with Midas Touch to turn enemies into Golden Poop, This does not work on mini-bosses and bosses. No longer drops black hearts like it used to. The achievement 'Sumptorium' is unlocked by defeating Delirium as Tainted Eve, When used, this will retreive the Tainted Forgotten's skeleton back to its owner's hands from any distance, Tainted Forgotten's Birthright effect. Stat Down becomes Stat Up, 'Bad Trip' turns into 'Balls of Steel' and 'Amnesia' turns into 'I can see forever', * astrology, astronomy, item room, treasure room, item room pool, blue glow, m, Balances out your main stats to bring the high and low stats closer to an average value, All future stat upgrading items will now instead spread out across all other stats. Tears continue to fire from your left eye, The laser deals damage equal to 1/7th of your tear damage, but very rapidly, The laser can apply status effects (e.g. Tears now have a chance to cause enemies to be magnetized, Magnetized enemies attract other enemies, tears (including Isaac's) and enemy projectiles, causing them to be pulled in towards them, Enemy tears that get pulled into other enemies will hurt them, You have a chance to fire a tear that marks enemies red and slow them, Marked enemies will be attacked by other enemies either until it is killed or it kills all the other enemies attacking it, Chance to fire a marking tear scales with your luck stat, This item has a different effect for each character. These can be smaller or big batteries, Upon use, Mom's Bracelet allows you to grab objects in the room and throw them, damaging any enemies which are hit for 40 damage, Most objects can be thrown including pots, rocks, poops, tnt etc, Pressing the activate button again will drop the object where you stand, which doesn't consume a charge of use, Allows you to remove the skull on top of Host enemies, turning them into the red version, *, arm, moms, ring, bracers, zelda, gold band, golden band, power bracelet, When used, this item spawns a Peeper familiar for the current room, which deals 12 contact damage per tick to enemies and leaves red creep in its path, Using this item removes Isaac's right eye, causing tears from this eye to deal x1.5 your normal tear damage, Using it more than once in the same room will spawn multiple Peeper familiars, Fired tears now have a chance to summon a rift when they land on the ground, The spawned rift sucks in enemies, projectiles and pickups and deals damage to enemies caught inside for 2 seconds, The chance to fire the rift tear can improve based on your luck stat. Unlocked from the 'U broke it!' - Gives the curse of the maze effect for the current floor. He won't respawn even if you move to a new floor, Will always match your current movement speed, UNLOCK: Unlock this item by defeating The Beast as Tainted Keeper, Only found in the Mausoleum/Gehenna II boss room, The item itself has no effect, but triggers the ascent through the backwards path towards the Home floor. These will more than usually harm you than help you. For more awesome indie content, subscribe to the channel here and follow me on Twitch for my livestreams!http://www.twitch.tv/pentahybridYou can also join ou. You can't use the Red Key to leave this room, The Red Key can be used to open the secret room in the Home floor, which is the method for unlocking alternative 'Tainted' characters, UNLOCK: Unlock this item by opening Mom's Box in the Home floor, Item Pool: Secret Room, Red Chest, Curse Room, Key Beggar, Mom's Chest. pink, purple, Spawns a familiar leech on the ground that hunts down enemies and heals you for half a heart each time it eats one, The Leech deals 1.5 contact damage per tick, * item room, treasure room, item room pool, grey, gray, worm, A bag that follows Isaac and drops a random heart, coin, bomb or key every 5-6 rooms (alternating, 5 rooms then 6, then repeats), Can drop any kind of heart, coin, bomb or key, UNLOCK: Unlock this item by beating the Dark Room with Eden, Item Pool: Item Room, Beggar, Secret Room, * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, secret room pool, item room, treasure room, item room pool, mysterious sack, multiple sacks, bag, pouch, purple, question mark, A large familiar black fly that bounces around the room, exploding on contact with enemies dealing 70 damage, Does not explode if it hits Isaac, however if it explodes on an enemy while Isaac is in range, he will take damage, Respawns after 10 seconds or by moving to another room, * item room, treasure room, item room pool, heart, smile, A green brain that launches in the direction you are firing your tears and will explode on contact with enemies, dealing damage and poisoning anything in the blast radius, Bob's Brain deals 100 damage and applies a poison damage over time effect, which deals double your tear damage per tick, Will hurt Isaac if he is in the blast radius. Displays a random cryptic message on the screen similar to the fortune machine ones. REPENTANCE - Skatole now prevents damage from eternal flies and Hush flies. (2% chance for the end of room drop to become a trinket), If a trinket has been smelted, it won't appear a second time unless the entire trinket pool is exhausted or you restart the run (e.g. This is to prevent a syngery like Dr. Fetus or a Golden Bomb giving you infinite resources, Isaac's shadow will follow closely behind him and when it comes into contact with enemies, will spawn friendly dark charger mobs, The chargers deal contact damage to enemies, and will be killed if it is hurt too much, Chargers disappear upon entering a new room, UNLOCK: Unlock this item by beating Greed Mode with Judas, Every time you kill an enemy a fly will be added to the Jar, allowing you to stack up to 20, Using the Jar of Flies will release all the flies that are currently in the jar as friendly flies that will damage enemies, A Loki familiar that follows Isaac and shoots tears 4 tears in a cross pattern, dealing a flat 3.5 damage each, Gives Isaac a familiar glass of milk that follows him and spills on the floor upon taking damage, After being spilt, the milk gives you a -2 Tear Delay (Tears up) for the rest of the room, When used, the D7 will restart the current room and bring back all enemies once again, enabling you to farm rewards that spawn at the end after beating the room, Can be used to generate infinite consumable combinations, gaining as many coins/keys/bombs as you need, This item has no effect in Greed Mode, Challenge Rooms and rooms that had no enemies in originally, If used in a Boss Room or Angel/Devil Room, you get teleported to another random room, which is reset instead of the boss/angel/devil room you were in, Enemies respawned by the D7 don't drop loot if they were champions and also don't grant score in daily runs, * dice, pip, die, turban, white, grey, gray, Makes Isaac very small like a baby, reducing his hitbox size, When used, Mom's Box will drop a random trinket on the ground, While held, doubles the effect of trinkets which make sense to be doubled (e.g. Build-defining, game-winning items that will likely carry any run that gets them. the lost item pool, cat, bone, pink, grey, gray, guppys paw, guppy paw, Gives a 1/3 chance for room clear rewards to become a normal or locked chest, and a 1/3 chance to reward nothing at all, Doesn't affect coins dropped after waves in Greed Mode, * curse room pool, red chest pool, red chest item pool, devil pool, devil room pool, devil deal, Based on the Steam Workshop mod (originally called Lightshot) created by Wyvern and TRPG, Pressing the CTRL key (R2 on PS4, RT on XB1, ZR on Switch) allows you to switch active items, Some items that give temporary effects like The Nail might deactivate if switched to the other slot, Added as part of the Afterbirth+ Booster Pack #4, UNLOCK: Unlock this item by entering every Shop from the first floor up to Mom's Foot (Depths 2) in one run, Grants you a shield when entering the Boss Room, which prevents damage from 1 hit, then disappears.